Category
Systemic Antibiotics - Others

Composition

Each tablet film coated contains : Metronidazole 500 mg
Trogyl suspension contains : Metronidazole 125 mg/5 ml

Metronidazole is an anti-infectious agent belonging to 5 nitro imidazole group. Antibacterial spectrum of metronidazole concerns exclusively anaerobic organism. It acts trichomoniacide and anaerobicide.

Indication

Urethritis and vaginitis due to Trichomonas vaginalis, amoebiasis, giardiasis due to Giardia lambliasis. Treatment of infections in which anaerobis bacteria have been identified : septicaemia, bacteremia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic cellulitis. Prevention of postoperative infections due to anaerobis bacteria.

Recommended Dosage
Intestinal amoebiasis (adults) : 750 mg, 3x daily for 5 – 10 days.

Hepatic amoebiasis (adults) : 500 – 750 mg, 3x  daily for 5 – 10 days.

Amoebiasis (children) : 35 – 50 mg/kg/24 hours, divided into 3 doses for 10 days.

Trichomoniasis (adults) : 2 g given either as single dose or in 2 divided doses or 250 mg, 3x daily for consecutive days.

Trichomoniasis (children) : 15 mg/kg/daily, divided in 3 doses for 7 – 10 days.

Giardiasis (adults) : 250 – 500 m, 3x daily 5 - 7 days or 2 g daily as single dose for 3 days.

Giardiasis (children) : 5 mg/kg, 3x daily for 5 - 7 days.

Anaerobic bacterial infection (adults) : 7,5 mg/kg every 6 hours, maximum 4 g daily for 7 – 10 days.

Contraindication

Hypersensitivity to Metronidazole, 1st semester pregnancy, patients with an established history of bone marrow depression.

Special Precaution

Patients Multiple sclerosis, collagen disease, TBC, AIDS and pregnancy.

see also Trogyl Infusion